Saturday, August 31, 2019

Principles of Health Care Practice Code of Conduct Essay

1.1 Introduction I am writing this report as a requirement for my HNC Health Care course which will be submitted to Christine Hughes. In this report I will be comparing and contrasting two health care professions, the two health care professions I have chosen to compare is nursing and social work. The report will be highlighting the principles of healthcare, such as Education and Registration, (still to finish) 1.2 Nursing Education & Registration To train to be a qualified nurse you undertake either a pre-registration diploma or degree at university this is normally a three year programme. Degrees and diploma programmes comprise of 50% theory and 50% practice, with time split between the higher education institute. Nursing is organised into four branches – Adult, Children, Mental Health and Learning Disabilities. During the first year of nurse training you are introduced to all of the key areas as part of the Common Foundation Programme. In the second and third year you focus on a specific branch, which runs the course. Registered nurses and midwives are responsible for assessing the needs of individuals, planning and implementing their care, and evaluating the effectiveness. The Nursing and Midwifery Council (NMC) is the statutory regulatory body for nursing, midwifery and health visiting in the United Kingdom. All nurses working in the UK, including those trained abroad, need to be registered with the NMC in order to practice as a nurse in the UK, of that care. All qualified nurses, midwives and health visitors are required to be members of the NMC in order to practice. If nurses, midwives or health visitors are found guilty of misconduct, the NMC has the authority to strike them off the register. www.nhscareers.nhs.uk, www.planitplus.net/careerzone/ www.nursingnetuk 1.3 Social Work Education & Registration Social work requires a professional qualification, currently a three year undergraduate honours degree or a two year Masters degree in social work that has been approved by the General Social Care Council (GSCC)). The course involves a combination of course work and a minimum of 200 days spent in practice settings providing the opportunity for lots of practical experience before you actually qualify. The social work qualification is suitable for social workers in all settings and sectors. As a student and once qualified you will need to register with the General Social Care Council (GSCC) which is responsible for regulating the workforce. Previous qualifications in social work including the diploma will continue to be recognised as valid social work qualifications. There are a variety of ways to enter the social work profession, according to age and previous experience. www.socialworkcareers.co.uk, www.planitplus.net/careerzone 2.1 The Nursing & Midwifery Council The NMC is the regulatory body for nursing and midwifery; there purpose is to improve the standards of nursing and midwifery care in order to protect the public through professional standards. NMC register all nurses and midwives to ensure that they are properly qualified and competent to work in the UK. They set the standard of education; training and conduct that nurses and midwives will deliver high quality healthcare consistently throughout their careers. NMC also makes sure that nurses and midwives keep all their skills and knowledge up to date and to uphold the standards of their professional code. They also investigate allegations made against nurses and midwives who may not have followed the code. Every registered nurse, midwife or health visitor must renew their registration every three years. Post-registration education and practice (Prep) is set by the NMC which is designed to help nurses and midwifes provide a high standard of practice and care. There are legal requirements set which must be met in order for there registration to be renewed. 2.2 General Social Care Council The General Social Care Council (GSCC) sets standards of conduct for social care employers and workers, this regulates the social care workforce including regulating social work their training and education. The GSCC is responsible for codes of practice for employers and employees in the care sector. Social Care Register is a register of qualified social workers, the registration will ensure that those working in social care meet rigorous registration requirements and will hold them to account for their conduct by codes of practice. Registered social workers are also required to complete post-registration training and learning activities before renewing their registration every three years. Post-registration training and learning requirements that all registered social workers must meet are every social worker registered with the GSCC shall, within the period of registration, complete either 90 hours or 15 days of study, training, courses, seminars, reading, teaching or other activities which could reasonably be expected to advance the social worker’s professional development. To keep a record of post-registration training and learning undertaken, and failure to meet these conditions may be considered misconduct. Continuing Professional Development in Nursing All registered nurses and midwives are required to take part in continuing professional development (CPD) in order to maintain their professional registration. This is part of the post-registration education and practice (PREP) requirements, set by the Nursing and Midwifery Council NMC. There are two types of PREP, 1. Practice standards and Continuing professional development standards. CPD is fundamental to the development of all health care practitioners, as it is important that nurses keep there knowledge and skills up-to date, to improve standards in the practice and to gain more qualifications. To meet the CPD standards nurses must undertake at least 35 hours of learning activity relevant to their practice every three years, to maintain a personal professional profile of their learning activity and to comply with any requests to audit how they have met these requirements. Nurses and midwives who do not comply with the Prep requirements will cause their registration to lapse and can no longer work as a registered nurse or midwife. These requirements must be met every three years, and are declared at the point that registration is renewed. 3.1 Clinical Governance Clinical governance is the framework through which the NHS is accountable for the continuing improvement of quality of professional standards whilst still safeguarding high standards of care, thereby creating an environment which aims for clinical excellence. It is to ensure that high quality and professional standards are being maintained, and that health professionals are competent to deliver care safely with the right training and skills. This protects the patients from risks and mistakes allowing them to have confidence and faith in their care providers. Clinical governance also ensures that practitioners are accountable for the quality of patient care they provide meaning that they are more likely to question their practice and seek to make it of more benefit to the patient’s health. If it is found that those standards are not being met or they have got complaints from individuals about there delivery of care, there will be someone answerable for the failures to maintain standards. Nurses are responsible for their own competence and if they carry out treatments or procedures then they will be deeming themselves to do so.

Friday, August 30, 2019

Bhopal Essay

This case was created by the International Dimensions of Ethics Education in Science and Engineering (IDEESE) Project at the University of Massachusetts Amherst with support from the National Science Foundation under grant number 0734887. Any opinions, findings, conclusions or recommendations expressed in this material are those of the author(s) and do not necessarily reflect the views of the National Science Foundation. More information about the IDEESE and copies of its modules can be found at http://www. mass. edu/sts/ethics.  © 2008 IDEESE Project. Bhopal Gas Disaster Chronology The timeline below documents the incidents leading up to and resulting from the 1984 Bhopal Plant Disaster. Use the key below to quickly find information on government measures relating to specific organizations, Indian national legislation, casualties, and economic conditions and profitability. A timeline documenting ensuing legislation can be found at the end of the main chronology. Key brown = central (India), state (Madhya Pradesh), or city (Bhopal) government measures relating specifically to UCC, UCIL, Bhopal plant, or immediate neighborhood of plant green = general India national legislation relevant to conduct of business red = casualty-producing plant incidents violet = economic conditions relevant to Bhopal plant profitability ___________________________________________________________________________ UCIL= Union Carbide (India) Limited UCC= Union Carbide Corporation 956 Indian Parliament adopts Companies Act of 1956 which requires affiliates of foreign companies to register as separate companies under Indian law and imposes limits on foreign investment and participation in all Indian companies. Union Carbide reduces its share of ownership in its Indian subsidiary (then called National Carbon Company (India) Limited from 100% to 60% in accordance with new Indian law by registering as an Indian company and selling shares to Indian citizens. All but one or two UCIL board members, all UCIL executives, and all regular or seasonal employees are Indian nationals. 1966 Indian market for fertilizers and pesticides is expanding as government adopts a range of policies, including efforts to increase yields and reduce post-harvest losses of crops to pests, to make India self-sufficient in food. India had depended heavily on outside food aid in earlier part of the decade, and government wished to end this. The domestic production of pesticides in 1966 is 14,000 metric tonnes, well short of what the government wants to supply to farmers. Union Carbide India Ltd (UCIL) establishes a new Agricultural Products Division to take advantage of growing Indian market for fertilizers and pesticides. Initial activity involves only local formulation (diluting â€Å"technical grade† concentrate to make products for sale to users). UCIL applies for license to carry out the whole production process in India. 2 of 19 1968 Government of India approves UCIL plans to build fertilizer/pesticide formulation plant in Bhopal. State of Madhya Pradesh leases land in the Kali Parade area of Bhopal for the plant to UCIL on a 99-year lease in an area zoned for industrial use. The area around plant is relatively unpopulated at time though there are two lakes nearby and the main Bhopal railroad station was about 2 miles from the plant site. Total population of City of Bhopal is estimated to be about 300,000 (the 1961 census put it at 102,000 but considerable in-migration from surrounding countryside had occurred). Adoption of India’s 4th five-year plan, to run 1969-74. Plan goals include reducing â€Å"unwholesome dependency on foreign agencies,† particularly foreign corporations. The Plan outlines goals of requiring foreign investors to enter into joint ventures rather than establish wholly-owned subsidiaries, and reaffirms requirements to train and employ Indian nationals at all levels of operation, to use made-in-India equipment and components whenever they are available, and to transfer technology to Indian affiliates. These requirements meant that the government was strongly interested in having chemical plants located within the country develop capacity to undertake all steps from raw material through intermediate chemicals through final product on-site rather than relying on imported intermediates. 969 Bhopal plant begins operating. Initial operations consisted of making raw fertilizer and formulating (diluting to usable strengths) pesticides with US-origin â€Å"technical grade† chemical concentrates. UCIL industrial chemists develop a method of producing alpha-napthol that UCIL anticipates being able to scale up to economically competitive prod uction volumes. UCIL is reconsidering its business plan as the large-scale making of alpha-napthol turns out to be more challenging than it anticipated. Government of India begins pressing UCC and UCIL to have UCIL plants shift from formulation using US-source chemicals to full production in India. It makes issuing an operating license for the Bhopal plant conditional on its using domestically-made alpha-napthol. Government of India establishes National Committee for Environmental Planning and Coordination. 1970 1972 1973 Indian Parliament adopts Foreign Exchange Regulation Act 1973. Among other strong controls on flows of money in and out of India it establishes a scheme for government control over Indian firms’ decisions on hiring foreigners as employees or contractors. Indian Government approves UCC-UCIL Design Transfer Agreement and Technical Services Agreement under which UCC will provide the basic process design of a plant capable of producing SEVIN (a carbaryl pesticide used on cotton and other crops) and training for Indian operators of plant. Design Transfer Agreement limits UCC to provision of the process design and materials specification. Detailing the design and building the plant are to be undertaken by Indians nationals employed by or contracting with UCIL. Government also uses powers to license technology imports to guide selection of suppliers of components for plant to Indian firms as much as possible. 3 of 19 Engineers employed by UCIL who will be involved in plant design visit UCC Technical Center in West Virginia to earn about US plant specifications and start process of adapting them to India’s conditions. 1974 Indian Parliament adopts legislation requiring that Indian companies partly owned by foreigners reduce foreigners’ ownership share. For companies with 60% foreign ownership, the new legal maximum is 50. %. UCIL complies by the end of 1978 through sale of additional shares of stock offered only to Indians; these shares were held by 24,000 different persons or entities, with the Government of India itself holding 25% of UCIL stock. Indian Parliament adopts Water (Prevention and Control of Pollution) and Air (Prevention and Control of Pollution) Acts. These establish the central government as the main standard-s etter while leaving enforcement to state governments. Both Acts increase penalties for causing pollution but do not specify any emissions or ambient standards. 975 New Master Plan for City of Bhopal establishes a separate district for â€Å"hazardous industry† in an open area 15 miles from center of town, and zone the area where UCIL’s plant has been constructed for commercial and light, non-hazardous, industry only. City authorities want UCIL to move its operations to this area. Indian Government licenses UCIL to produce up to 5,000 tons of carbaryl pesticides a year in Bhopal plant UCIL hires Humphreys and Glasgow Consultants Private Limited, an Indian subsidiary of Londonbased Humphreys and Glasgow, to detail the plant design and supervise construction. 976 Madhya Pradesh Town and Country Planning Board classifies the UCIL plant as â€Å"general industry† rather than â€Å"hazardous industry. † This allows plant to stay in its established location rath er than move to Bhopal’s new hazardous industry zone. Bhopal plant begins production of pesticides and begins $2. 5 million project to expand alphanapthol production unit to accommodate Sevin production. India hit by drought; farmers need loans from government to ride out the loss of harvests. They also cut back on pesticide purchases. 1978 Bhopal plant’s new alpha-napthol unit’s components fail soon after startup. 2 million reconstruction project begun. Production of pesticides continues using alpha-napthol imported from UCC’s US plants. 31 Oct 1977 4 of 19 UCC and UCIL decide to shift Bhopal plant to methyl isocyanite (MIC) process to produce SEVIN because parent UCC regarded this process as more economical and efficient than its previous way of producing it. New Bhopal MIC unit based on design of UCC’s MIC unit in Institute, West Virginia. (See separate page on alternative methods for production of SEVIN or similar carbamate pesticides. winter P rogress review of Bhopal project at UCC headquarters. Concerns about cost of building plant and reduced estimates of potential pesticide sales lead to consideration of whether Bhopal project can be scaled back. Decision is to continue as construction is too far advanced. Welding spark ignites nearby chemicals because welder unaware of and supervisor did not point out nearby flammables. Fire causes Rs. 6. 2 million ($730,000) in property damage, but no injuries to workers. 20 UCIL engineers sent to UCC’s West Virginia MIC plant for training in plant operation and safety. UCC engineers sent to India for pre-startup inspection of Bhopal plant report multiple deficiencies in safety measures. They also advise UCIL management of need to develop contingency plan for alerting and evacuating nearby population in event of major gas leak. UCIL management later reports it had developed such plans; city and state government officials claimed in 1984 that they were not aware of any such plans. UCC Eastern Division brings up question of Bhopal plant at a global strategy meeting because of concern that it, like Institute WV plant, is too large for the market. Proposals to export part of Bhopal plant’s production are not adopted because of potential negative effects on UCC subsidiaries in other countries. UCC sends 8 US engineers and technicians to Bhopal plant to assist with startup and early operation of MIC unit. 1980 Government loans to farmers come due. Farmers shift to less expensive pesticides. Many of the newer pesticides are synthetic pyrethroids that are also safer in Indian conditions than carbaryl types like Sevin. Indian Government upgrades National Committee for Environmental Planning to cabinet-level Department of Environment. Both national and most state governments (including Madhya Pradesh) have Pollution Control Boards to inspect and enforce environmental laws. March Government approves UCIL application to retain 1 UCC engineer through 31 May 1981; renews approval through 31 May 1982 and then to 31 December 1982. 7 of the 8 UCC engineers and technicians sent from West Virginia return home. The remaining engineer continues to serve as plant manager until June 1982, then remains as a consultant. 24 Nov 1978-79 1979 June 5 of 19 fall A second UCC engineer team visits the Bhopal plant and repeats warnings about ack of contingency plan. Rebuilt alpha-napthol unit started up; fails again and is shut down. Alpha-napthol imports continue. Bhopal plant returns a modest profit for the year. National census puts City of Bhopal population at 895,815. Significant populations of recent arrivals from the countryside have settled in shanty towns near UCIL plant. 1981 June UCIL/UCC review of Bhopal plant operation show s that the variable cost of producing alphanapthol in Bopal is 4x the US cost and the variable cost of producing SEVIN in Bhopal are 3. 5x US costs. UCC and UCIL are both aware that new-formula pesticides coming onto market in India and other countries are likely to reduce demand for SEVIN. UCC wants UCIL to import MIC from UCC plant in West Virginia; Government of India refuses permits because it wants the making of MIC undertaken in India. 24 Dec 1 supervisor and 2 workers exposed to phosgene leak during a maintenance operation; one of the workers dies from effects of phosgene inhalation. UCIL management says he was at fault for removing his gas mask; workers claim supervisors gave insufficient warnings. Accident reported to UCC; UCC response plan includes additional training and some design changes. 1982 uncertain 10 Feb Feb UCIL notes growth of shantytowns near the Bhopal plant and asks the city to establish a â€Å"greenbelt† zone around it to prevent further shantytown expansion. City does not act. 25 workers injured when a pump seal fails and significant quantities of MIC, phosgene, and hydrochloric acid gases escape into plant. Some treated on-site; 16 sent to local hospital Workers help a local journalist get into plant; he observes and writes about poor condition of plant and lax safety routines. Local newspaper publishes the story but its warnings that a massive leak is likely are ignored. India Labor Department investigates the Dec. 1981 fatal accident and recommends corrective measures. Bhopal plant is operating at less than half capacity because of weak market for its products. Local competitors making cheaper pesticides continue gaining market share. spring Either UCIL asks UCC to send engineering team to inspect plant, or UCC does on own initiative (accounts vary, usually consistently with author effort to show UCC was or was not in close control of plant during the post-disaster litigation). 6 of 19 2 April May 3 electricians suffer minor burns when one drops a screwdriver into an electrical panel and it shortcircuits. State inspectors recommend better insulation of circuits. UCC engineers inspect Bhopal plant, issue Operational Safety Survey on conditions in plant, warn there is real danger of a runaway reaction; suggest measures to avert danger UCIL management report s to UCC on follow-up, saying they will undertake all suggested measures, but do not act on the recommendation to increase the range of the firewater spraying system from 15 meters to 35 meters so it can reach the top of the MIC vent pipe. The last UCIL communication on followup, dated 26 June 1984, says all changes have been made except one to the SEVIN feed tank, which will be completed when the needed control valve is delivered in about a month. summer Jagannathan Mukund, Indian citizen trained at Institute WV plant, replaces US national Warren Woomer as plant manager. UCIL has to admit failure of efforts to scale up alpha-napthol production; alpha-napthol unit shut down as too unprofitable to run. Worker transfers begin. Aug Sept fall 6 Oct Splash of liquid MIC at plant injures a chemical engineer UCIL applies for extension of its Foreign Collaboration Agreement with UCC through December 1987 so it can continue importing alpha-napthol. Indian government approves UCIL application for renewal of Foreign Collaboration Agreement with UCC, but only to 1 Jan 1985. Leaks of MIC, hydrochloric acid, and chloroform injure 3 workers seriously enough to require brief hospitalization; 15 others less affected are given first aid at plant. Some panic in neighboring shantytown. State inspectors note several violations of normal operating procedures and recommend measures including red tags on equipment that should not be used. Labor unions complain to Madhya Pradesh Ministry of Labor about conditions in plant. Also begin occasional public demonstrations. Madhya Pradesh state labor ministry inspectors inspect plant but they are mechanical engineers with limited competence to assess safety of chemical plants. Labor Ministry officials do enter complaints with courts, but these will not be taken up for some time owing to long list of pending suits. Madhya Pradesh minister of labor says the plant is safe and berates opposition for its worries during question time in a December session of the state legislature. 31 Dec Warren Woomer, the last remaining American employee, leaves Bhopal plant. 7 of 19 1983 Various cost-cutting measures undertaken. Staff morale declines through the year as layoffs and resignations take effect. Experienced workers leave and are replaced by less experienced workers from other units of Bhopal plant or other UCIL plants. Madhya Pradesh State Pollution Control Board requires companies to declare what they are emitting into the air. UCIL declared carbon dioxide only, not the other gasses (including phosgene and MIC) that occasionally leak. Board lacks sufficient inspectors to follow up, even after animals die from drinking water from a stream just outside the plant polluted by fluid runoff from the plant. Sept. fall Dec. Chief of National Pollution Control Board visits plant area while in Bhopal. Orders UCIL to fix flaws in effluent evaporation pond that permit leaks onto adjacent land. UCIL complies. Proposal to salvage investment in Bhopal plant by converting part of it to produce new carbofuran pesticide and supply it to India and other markets are rejected as economically unfeasible by UCC. Jumper pipe connected between pressure valve header and relief valve header on MIC tanks to simplify maintenance. Bhopal plant manager Jagannathan Mukund given UCC safety award for operating 12 months without serious incident. 1984 Bhopal plant operating at 1/5 capacity owing to weak demand. Losses near $4 million since 1980. Successive reductions in personnel mean only 1 supervisor and 6 workers are present on each shift in the MIC unit (company guidelines state that the MIC unit should have 3 supervisors and 12 workers on each shift). Training of supervisors and workers has become less rigorous. April Madhya Pradesh government legalizes the shanty towns that have grown up just outside UCIL plant since 1978 by granting dwellers certificates of ownership of the land they occupy. Bhopal population estimated to be close to 900,000 and the shanty towns are notably larger than they had been in 1981. UCC approves UCIL proposals to write off the alpha-napthol unit, sell rest of Bhopal plant while retaining MIC unit, reduce UCC ownership share of UCIL to 40% so UCIL can be more independent. Neither the UCC share reduction nor the plant sale had been carried out by December. May June or July Bhopal Town Planning Board lists 18 factories as â€Å"obnoxious† and therefore to be monitored particularly carefully. UCIL’s Bhopal plant was not included on the list. Sept UCIL engineers inspect plant, report to UCIL top management that 1) gas scrubber is functioning poorly, 2) there are poor communication between plant production and maintenance staff, 3) workers lack instruction on what do in event of runaway reaction, 4) safety meetings are held only half as often as specified in company rules. 8 of 19 UCC engineers survey MIC plant in Institute, West Virginia. They report concerns about some aspects of plant operation there and possibility of a runaway reaction in the MIC storage tanks (larger than the tanks installed in the Bhopal plant). Oct UCC considers idea of dismantling Bhopal plant and shipping equipment to Brazil or Indonesia. Asks UCIL to draw up feasibility study and cost estimates. UCIL reports back 29 Nov. Question of what to do is pressing because the plant will have no source of alpha-napthol when UCIL’s Foreign Collaboration Agreement with UCC expires on 1 Jan 1985. 7-22 Oct Remaining phosgene and methylamine stocks at Bhopal plant are used up in making a last batch of MIC. 42 tons are put into Tank E610; about 20 tons into Tank E611. UCIL plan is to withdraw it a ton at a time In November and December and react it with alpha-napthol to produce SEVIN. The storage tanks are isolated and the MIC production unit is shut down for maintenance after the batch is finished; MIC unit production workers are assigned to other tasks. 31 Oct Curfew imposed in Bhopal after inter-communal riots sparked by news Sikh guards had assassinated Prime Minister Indira Gandhi. Plant activities curtailed for several weeks because curfew affects ability of second shift to leave work and of third to arrive for work on time are affected. MIC drawn down in small batches. Nov last week of Nov. According to later testimony of plant workers, the position of second-shift maintenance supervisor was eliminated. Dec condition of plant safety systems at start of second shift Safety System vent gas scrubber (uses caustic soda to neutralize toxic gas exhaust from MIC plant and storage tanks before release thru vent stack or flare) flare (burns toxic gasses to neutralize them) Condition on 2 Dec 1984 on standby since MIC not in active production but could be activated b y plant operators in event of need insufficient capacity to burn large volumes of escaping gas; shut down in November for replacement of a corroded pipe; MIC process vents rerouted to the vent gas scrubber while repairs proceed shut down June 1984 and coolant (Freon) drained for use elsewhere in plant refrigeration system (keep MIC at temperatures of 0-5 degrees C (32 to 42 degrees F) where it is less reactive) firewater spray pipes (to control escaping functional but insufficient height to reach gasses, cool over-heated equipment or douse top of vent stack fires) 9 of 19 afety valve between MIC storage tanks and MIC holding tank in SEVIN production area operational; designed to hold MIC in at normal pressures and release it if pressure too high. There are 2 competing versions of events on December 2nd between 9 and 11 pm. The first is preferred by most authors who have studied the events; the second is offered by only a few. *See note at end for more information about the controver sy. Divergent accounts of how water entered Tank E610 Version 1: water-washing of pipes 8-9 pm Second-shift production superintendent orders MIC plant supervisor to flush several pipes running from the phosgene system to the scrubber via the MIC storage tanks. MIC unit workers are in charge of the flushing, but maintenance department is responsible for inserting the slip bind (a solid disk) into pipe above the water washing inlet as plant manual requires. These take 30 minutes-2 hours to install. The MIC unit workers were apparently not aware that installation is a required safety procedure, and slip bind is not installed first. Temperature of MIC in tanks is between 15 and 20 degrees C . 9. 30 Water washing begins. One bleeder valve (overflow device) downstream from the flushing was blocked so water did not come out as it was supposed to. It accumulated in the pipes. A worker shut off the water flow but the plant supervisor ordered that the washing resume. By then water had risen past a leaking isolation valve in the lines being washed and got into the relief valve pipe 20 feet above ground. by 10. 30 pm Water has flowed from the relief valve pipe through the jumper pipe into the process pipe through valves normally kept open. Water gets Water washing proceeded as described but none of the water used for washing traveled far enough down the right pipe to enter Tank E610. Version 2: sabotage 10 of 19 through an open blow-down valve that is part of the nitrogen pressurization system. It is unclear whether the valve had been left open or had failed to fully seal when last closed. Water then flows into tank E610 via a normally-open isolation valve. 10. 30-10. 45 pm Second shift goes off work; third shift comes on. Washing continues after second shift worker briefs third shift worker on progress of the job. around 10. 30 pm A disgruntled worker removes a pressure gauge on a pipe leading to Tank E610 and connects a water hose to the coupler. Water enters Tank E610 Shared account of responses to detection of problems 11 pm Third shift control room operator notices pressure gauge connected to Tank E610 has risen from a reading of about about 2 psi at the start of the shift to 10 psi. This is within the normal 2-25 psi range, so arouses no concern. Control room lacks any reliable way of monitoring tank temperatutre. about 11. 30 pm Workers in area notice MIC smell, see MIC leak near the scrubber. Find MIC and dirty water coming out a branch of the relief valve pipe on the downstream side of the safety valve, away from the tank area. They set up a water spray to neutralize the leaking MIC and inform control room personnel of situation and their actions. They then take their regular tea break, continuing to discuss the situation and what they should do next. 3 December about 12. 15 am Control room operator notices that control room pressure indicator for Tank E610 reads 25-30 psi about 12. 30 am . Control room operator notices that needle on pressure indicator for Tank E610 is pinned to the maximum reading of 55 psi. Control room operator goes out to tank area to check gauges on tank. While in tank area he hears a safety valve pop, hears rumbling in tank, and feels heat emanating from it. Returns to control room to engage the gas vent scrubber. Caustic soda does not flow as it should. A cloud of gas escapes from the scrubber stack. by 12. 40 am Plant supervisor suspends operation of the MIC plant, turns on the in-plant and external toxic gas sirens. External sirens audible in nearby neighborhoods are turned off after about five minutes. Operators turn on the fire water sprayers but water cannot reach the gas cloud forming at the top of the scrubber stack. Efforts to cool Tank E610 with the refrigeration system fail because the Freon had been drained. Gas escapes for about 2 hours. 11 of 19 efore 1 am Plant supervisor realizes that tank E619, the designated spare, is not empty, so workers cannot relieve the pressure in E610 by transferring any MIC to E619. by 1 am gas smell is obvious outside the plant; nearby residents awake at the time or awakened by noise and sm elling the gas odor start fleeing in panic. 1. 30 am Bhopal police chief informed of leak and panic by an on-duty officer who ran to his house; no significant police mobilization follows. about 2. 30 am Bhopal plant external siren for warning the neighborhood is turned on again about 3 am Army engineer units with trucks are mobilized after a retired brigadier general requests help evacuating workers from his factory near the UCIL plant (but not under the strongest gas concentrations). Army unit then expands operations to assist general populace by transporting injured to hospitals and clinics. Some mobilization of city ambulances. Medical personnel hearing of situation head to hospitals and clinics. before 8 am Madhya Pradesh governor orders closure of plant plus arrest of plant manager and 4 other employees. afternoon Head of India Pollution Control Board informed of accident. Efforts to learn details from Madhya Pradesh Pollution Control Board fail because phone calls cannot get through. Phone conversation with UCIL office in New Delhi (also unable to get phone calls through to the plant) provides some information about possible causes. ate afternoon Indian Central Bureau of Investigation takes control of plant and UCIL records there. CBI agents begins interviewing plant supervisors and workers; bar entry by anyone else, including other UCIL employees. Dec Many government offices and businesses in Bhopal closed; dead buried or cremated in accordance with their f amilies’ religious traditions; initial treatment of injured proceeds 18-19 Dec Under government supervision the MIC still in storage at the UCIL is plant is neutralized by combining with alpha-napthol to make finished pesticides. Local population leaves town as a precaution. 1985 July 1985-98 1994 1998 Madhya Pradesh government rejects UCIL application for renewal of operating license. Plant closed Some work on cleanup of plant site by UCIL. UCC sells its share of UCIL to McLeod Russell (India) Limited. McLeod Russell renames UCIL Eveready Industries India, Ltd. State of Madhya Pradesh takes over plant site from Eveready Industries. 12 of 19 *Note on the two versions of how water reached storage tank 610. Timelines of the alternate possibilities are constructed from the works of several Indian authors who collectively used interviews with plant staff, court depositions by plant staff, interviews with local residents and officials, UCIL executives and UCC technicians, and UCIL or UCC documents obtained during the post-disaster litigation. Most of the detail comes from Paul Srivastava, Bhopal: Anatomy of a Crisis (Cambridge, MA: Ballinger, 1987),and Sanjoy Hazarika, Bhopal: The Lessons of a Tragedy (New Delhi: Penguin Books India Pvt Ltd, 1987), who take different views but are careful to acknowledge areas of uncertainty. The initial exposition of the water-washing explanation was provided in an Indian government report, S. Varadarajan et al. â€Å"Report on Scientific Studies in the Factors Related to Bhopal Toxic Gas Leakage (New Delhi: Council of Scientific and Industrial Research, Dec 1985). The sabotage theory was developed by consulting engineers from Arthur D Little, Inc. commissioned by UCC to investigate the causes. It was publicly laid out in Ashok S. Kalelkar, â€Å"Investigation of Large-Magnitude Incidents: Bhopal as a Case Study,† in I. Chem. E. Symposium Series No. 110 The Institution of Chemical Engineers 1988, p 561. Version 1 in the timeline, favored by local and international trade union representatives, local activists, the Indian government, transnational environmental and consumer organizations, and most technical experts (see Chemical and Engineering News 4 July 1988) is based on known water-washing activities. Proponents of version 2, favored by UCC after its investigators were able to visit the plant in early 1985, point out that the water washing occurred a good distance away from the storage tanks and there is no evidence water ran through the connections from the washing area to the storage tanks. They also point to evidence that the pressure gauge on the pipe leading into Tank 610 was noticed to be missing when tank area was surveyed before 10 am on Dec 3rd and a replacement gauge was installed. The most thorough summary of this version is Themistocles D’Silva, The Black Box of Bhopal 1993 who does state clearly that he was a UCIL employee – though not at the Bhopal plan t – in the 1980s. ) Even if sabotage were involved, no commentator thinks the saboteur was trying to cause a catastrophic gas leak; knowledge of safety hazards among the workers was spotty enough that very few of them understood the full effect of introducing water into the MIC storage tanks. The controversy was sharpened in the course of the extremely acrimonious litigation between the Government of India and UCC. UCC first raised the sabotage allegation in 1985 and repeated it in 1988 but never named the suspected saboteur. A worker believing he is the suspect publicly challenged UCC to name the suspect and denied that he had any involvement in sabotage. UCC planned to wait until the trial before the Indian Supreme Court to do so; out-of-court settlement made that unnecessary and it never publicly revealed the full basis of its suspicions. In a FAQ section of its website on Bhopal (www. bhopal. com) Union Carbide’s answer to the question of if there was sabotage why hasn’t the company named anyone, it says that the name is known to Indian enforcement authorities. While a useful way to avoid libel suits, the continuing refusal to provide a name response is interpreted as weakening UCC’s claim by those who reject the sabotage theory. Notice that the contending versions of events between 9 and 11 pm on December 2nd only provide different explanations of how water got into MIC storage tank 610. Everyone who has studied the disaster agrees that the injuries to neighboring residents were caused by an unneutralized cloud of leaked gas that escaped through the vent, and that the reaction producing this cloud was triggered by water contamination. Though the concrete shielding of the storage tanks cracked above Tank 610 (indicating that its temperature 13 of 19 got above 400 degrees F), the tank itself was found to be uncracked when inspected after remaining contents were neutralized and removed in mid-December 1984. There is no substantial disagreement about the conditions of the safety systems that night or on the responses of the supervisors and workers after the small MIC leak was noticed around 11. 30. Nor is there any significant disagreement about the inadequacy of contingency plans for in-plant response and evacuation of neighboring settlements, the poor communication about hazards with city and state authorities, or the insufficiency of warnings to surrounding settlements when the gas cloud formed. Descriptions of the extent and timing of action by city officials, state officials, army units in Bhopal, and national government officials also vary very little; controversy about government response is focused on the adequacy of actions in the days, months, and years following the disaster. 14 of 19 Bhopal Gas Disaster Chronology: Ensuing Litigation 985 March UCC and Government of India investigatory teams conclude independently that runaway chemical reaction causing MIC gas cloud was caused by water getting into Tank 610 Indian Parliament adopts Bhopal Disaster Relief Act making Indian government the sole legal representative for all victims of the Bhopal disaster. US Federal Dist rict Court consolidates all lawsuits pending in US about Bhopal gas leak into one case, Union of India v. Union Carbide Corporation. rest of year Victims and victim advocates complain about lack of effective relief. rest of year UCC stock declines; total stock value of company in December put at approximately $3 billion. UCC sells off assets (mainly petrochemicals and consumer product divisions) for $3. 5 billion and borrows $2. 8 billion to fend off $5. million takeover bid by GAF (General Analine and Film, another specialty chemical maker) 1986 Government of India lawyers and UCC lawyers begin discussion of an out-of-court settlement. Union Carbide proposes a settlement amount of $350 million under arrangements that it estimates will generate a fund for Bhopal victims of between $500-600 million over 20 years. Government rejects this offer as insufficient. Indian and foreign activist groups supporting victims have already publicized their own estimates contending that damages are at least $3 billion if loss of animals, loss of income from inability to work, loss of business in the weeks after the gas release, and related damages are also taken into account. April U. S. Occupational Safety and Health Administration proposed a $1. 4 million fine against Union Carbide Corp, based on results of its September 1985 inspection of five of 18 plant units at Institute, West Virginia. OSHA alleges 221 violations of 55 health and safety laws, listing 72 of the 221 as â€Å"serious† (the category for violations creating conditions in which there is substantial probability of death or significant injury. US Federal District Court rules on a preliminary motion in Government of India v. Union Carbide Corporation; invoking forum non conveniens doctrine it determines that trials relating to injuries suffered in the Bhopal disaster should be held in India. March May 5 of 19 Sept. Dec. Government of India proceeds against UCC in District Court in Bhopal, seeking $3 billion in total compensation for 630,000 persons in Bhopal area. Bhopal District court orders UCC to hold $3 billion in unencumbered assets as collateral while lawsuit pending. This to prevent consc ious a run-down of assets, rumors of which were rife in USA and India at the time. UCC offers $50 million, then $80 million in compensation, amounts derived from typical Indian settlements. Amounts widely criticized, viewed as insulting by victim groups, rejected by Government of India. 1987 Jan rest of year 1988 Victim lawsuits continue in Indian courts. State of Madhya Pradesh also files criminal charges against Warren Anderson, then CEO of UCC, and several UCIL executives or plant supervisors for their roles in causing the disaster. 1989 Feb Under prodding by Indian Supreme Court, UCC and Government of India agree to a $470 million settlement of all Bhopal gas leak-related claims. Supreme Court endorses settlement, making it binding on both parties. It also grants immunity against criminal charges arising from the gas leak. The $470 million is paid to the Government of India as sole legal representative of the victims. 36 special courts established in Bhopal to deal with applications for compensation Value of UCC stock rebounds somewhat with news of settlement. UCC CEO Robert Kennedy (replaced Anderson in 1987) completes reorganization of UCC into a holding company with 3 main divisions: chemicals and plastics, industrial products, carbon products. 1990 Oct 2 groups of victims file class action suits in Texas alleging that India failed to represent them adequately because of government agencies’ ownership of UCIL stock, and therefore did not secure them sufficient compensation. Consistent with 16 of 19 US Court of Appeals upholds US District Court ruling that Bhopal disaster litigation should proceed in India rather than the USA. UCC sells off last petrochemicals and consumer products divisions norms of mutual respect for court decisions, US courts refuse to review the Indian Supreme Court’s ruling. Nov. Government of Madhya Pradesh submits final list of names of victims to be compensated for injuries suffered in gas leak to Indian Supreme Court. Total deaths attributable to gas exposure put at 3,828. 1991 Oct Indian Supreme Court confirms compensation settlement, issues ruling modifying certain parts of 1989 judgment. These include UCC establishment of a trust fund to support a new hospital in Bhopal to treat victims’ ongoing health problems and revoking immunities from criminal charges. District Sessions Court in Bhopal reinstates charges of â€Å"culpable manslaughter not amounting to murder† and lesser charges relating to voluntary infliction of harm against Warren Anderson and 8 UCIL executives or supervisors. 1992 Apr 1993 Mar. NY Times reports that India has paid 700 Bhopal claims; government attributes delay to complexities of verifying the claims given chaotic record keeping at the time. Victim advocates blame on government incompetence. US Supreme Court declines to review federal court decisions in 1990 cases dismissing suits against India. UCC establishes the trust fund. Oct. 1994 Apr Nov Dec Indian Supreme Court approves UCC plans to sell its 50. 9% share of UCIL; proceeds to be given to Trust Fund for hospital in Bhopal. UCC completes sale of UCIL to McLeod Russell (India) Ltd. of Calcutta for approximately $93 million UCC provides initial payment of proceeds into Trust Fund. Ten-Year Impact of Bhopal Disaster on UCC year ending 31 Dec. 1984 total assets $10,518 million capital $7962 million year ending 31 Dec. 1994 $5028 million $2479 million 17 of 19 net sales net income R&D spending employees [from UCC annual reports] $9608 million $323 million $265 million 98,666 $4653 million $379 million $136 million 12,004 1999 Jan 2000 Mar Class action suit, Bano v. Union Carbide Corporation, filed in US Federal Courts by Haseena Bi and other organizations representing residents of Bhopal seeking compensation for gas-leak related injuries and for further harm from exposure to contaminants afterward under US Alien Tort Claims Act. US District Court dismisses Bano case UCC completed payments to Trust Fund, which now totals $100 million. Construction of hospital is complete and physicians and other staff being recruited. Aug 2001 Trust Fund-financed Bhopal Memorial Hospital and Research Centre begins treating patients. 2004 July Indian Supreme Court orders government to release all additional settlement funds to the victims. Indian newspapers reports after all claims were paid there was still about $327 million in the fund because of interest earned while the money was in escrow pending distribution. Indian nationals file Janki Bai Sahu v. Union Carbide Corporation in US Federal District Court. Suit seeks compensation for personal injuries claimed to be result of exposure to contaminated water and remediation work at former UCIL plant after the gas leak. Nov 2005 Apr Indian Supreme Court grants Indian Government Welfare Commission for Bhopal Gas Victims request for an extension of deadline on distribution of remaining funds and extends it to April 30, 2006. Indian newspapers report that approximately $390 million remains in the fund. US Federal District Court dismisses two of the three compensation claims raised in the Janki Bai Sahu case. Dec 18 of 19 2006 Sept Indian newspapers report that the Welfare Commission for Bhopal Gas Victims has completed paying out all claims to listed victims of initial gas leak. The Second Circuit Court of Appeals in New York upholds the dismissal of claims in Bano vs. Union Carbide Corporation. Federal District Court dismisses remaining claim in Janki Bai Sahu case. 2007 Mar A group of Indian citizens files a new class action suit, Jagarnath Sahu et al. v. Union Carbide Corporation and Warren Anderson, seeking compensation for damage to six individual properties allegedly polluted by contaminants from the Bhopal plant, as well as the remediation of property in 16 colonies [squatter settlements] adjoining the plant. Federal Courts issue a stay [suspension] of proceedings pending resolution of appeal in Janki Bai Sahu case as the issues in litigation are so similar. -end- Nov 19 of 19

Thursday, August 29, 2019

Provisional Measures Assignment Example | Topics and Well Written Essays - 250 words

Provisional Measures - Assignment Example Provisional measures in international arbitration can be dictated for the purpose of: a) Preserving the legitimate rights of the requesting party before the decision on the merits of the case (Interim Award ICC 8786). b) Ensuring the security of amount incurred in dispute in the arbitration process. c) To preserve or inspect any property that relates to rage dispute in the arbitration process. d) Provisional injection of a receiver. e) Any other provisional measure that the Court deem otherwise. Ordering a party to provide security (Charles Construction Co v Derderiamn). Question 24 In cases of urgency, the arbitral tribunal may, upon application of a party, order provisional measure, as it deem necessary. Such normally happens when preservation of evidence or assets is the primary goal. Ideally, arbitral tribunal has such provision to prevent other courts from supping the powers of arbitral teams. Lastly, tribunal always consults with parties before ordering interim measures but sometimes they may not if parties fail to agree. Question 25 a) In the Van Uden Case of 1998, European Court had to determine whether the provisional measure was necessary for Brussels Convention while arbitration was pending in Netherlands. b) Yes. The statement is relevant because it provides a platform that discourages courts from supping the powers of the arbitral tribunal, an occurrence that can significantly influence the outcome of the arbitration process. In other words, the courts can only issue provisional measures when the tribunal cannot do so.

Wednesday, August 28, 2019

The processes that occur in the Network when you Essay

The processes that occur in the Network when you - Essay Example There are several processes that are running concurrently, both at server and client ends, to make this communication a success. A thorough knowledge of these devices and their roles, protocols and associated technologies, at various levels of the network, is required for understanding the process that take place in a network for communication to occur successfully. Analyzing the process at various layers of a network demands a methodical comprehension of a ‘broad brush’ picture of the communication channel and protocol stack that might be at work behind the scene. More often than not, access to private networks, like the X-Stream server from our home or some other remote location is materialized through Virtual Private Network (VPN) technology. VPN is used to access a private network, like a university Learning Management System (LMS), over a public network like the Internet. When a student access X-Stream Server over a public network, this implementation of VPN is know n to be an ‘Access VPN’. VPN ensures a secure access to the private resource through implementation of security at various layers of the communication channel. ... rs used to define communication spectrum over the TCP/IP suit of protocols includes; Application Layer, Host to Host Layer , Internet Layer and Network Access Layer. The process that occurs on the network is mainly the study of data as it travels through the TCP/IP stack because WAN is only used as a vehicle to carry data and no significant processing is done as far the data is concerned. There are several important protocols that forms a part of the TCP/IP protocol suite which includes FTP, TFTP, VoIP, HTTP, ICMP, UDP, ARP and RARP etc. Moreover the RIP and OSPF are also the part of TCP/IP protocol suite which ensures the routing of the information over a network. From a user’s perspective the process that occur on a network starts with the use of application software that can talk to a underlying network e.g. a web browser that uses HTTP to make things happen for a user. Comer refers this as the application level internet service and states, â€Å"From a user’s point view, the internet appears to consist of a set of application programs that use the underlying network to carry out useful communication tasks†(3). Moreover the session of communication instance is maintained at the Application Layer, however these session are not logged by HTTP. â€Å"Each HTTP request is self-contained; the server does not keep a history of previous request or previous sessions† (Comer, 490). At next level the processes to ensure and enforce the data integrity, correctness and reliable packet delivery are guarded by the Host to Host layer. This layer also segments and sequences the continuous stream of data that leaves a user end and reassembles it at server end while acknowledging the receipt of each segment. â€Å"As each segment of data is received at the destination, an

Tuesday, August 27, 2019

Corporate Finance Essay Example | Topics and Well Written Essays - 500 words - 6

Corporate Finance - Essay Example Due to recessionary conditions and down side of economy, there is no immediate chance of recovery. Accordingly, Qantas Airways, which has leveraged beta of 1.25 is certainly a more risky company compared to any other company in the table. Above table suggests that business risks associated are lowest with Telstra Corp. and Coca Cola companies for having lowest beta of 0.16 and 0.15 respectively. Highest business risks are associated with BHP Billiton and Rio Tinto with beta of 0.52 and 0.43 respectively. As table indicates for the companies where finance risks are low (like CSL and BHP Billiton), business risk is high and the companies with high finance risk (like Coca-Cola and Telstra), business risk is low. Thus when we compare business risk with finance risk, we find that both are not consistent. Further, comparing the figures of shareholder’s return of BHP Billiton and Coca Cola, we find that both have given almost same returns; however, there is a vast difference between their business risks and financial risks profiles. Obviously, they are following Modigliani and Miller theorem that value of the companies are independent of its capital structure. 3. BHP Billiton and Rio Tinto though belong to the same industry sector; they have vastly different debt-equity ratios. Rio Tinto is a high leveraged company and its return on equity in percentage terms is less than that of BHP Billiton, which indicates that servicing cost of debt lowers down the percentage return on equity. In other words we can say that higher leveraging does not bring any additional return to the equity holders. Total shareholder’s return too in case of Rio Tinto is only slightly less compared to that of BHP Billiton’s shareholder’s return. Despite large percentage difference in return on equity, there is not a proportionate difference on the value of total shareholders return. In short, above set of Australian companies do not seem to

Monday, August 26, 2019

Metropolitan Police and are they Racist Assignment

Metropolitan Police and are they Racist - Assignment Example This approach is not only unacceptable, but also shameful. Therefore, this research aims to find out with the help of data whether this hypothesis is true or not. Analysis is made on the basis of a detailed discussion about the history of racism and its roots. It then looks into various incidents of racism that have taken place in history and Police’s involvement in them. Besides, it takes a closer look at the August riots and its various causes. In the end, a conclusion is presented that sums up the discussion and gives out some recommendations on the basis of it. TABLE OF CONTENTS EXECUTIVE SUMMARY 2 TABLE OF CONTENTS 3 INTRODUCTION 4 Research Background 4 Aims and Objectives of the research 4 Rationale for the selection of the research 5 Research Question 5 Hypothesis 6 Review of the Key References 6 Key references for this study include the website of metropolitan police service and BBC website from which statistics of the August riots have been taken. Discussion about his tory of racism and introduction to institutional racism and its history, Macpherson and Scarman report and different incidents of police acting racist have been taken from various books and journal articles. These books include Racism and Borders: Representation, Repression, Resistance, Institutional Racism: A Primer on Theory and Strategies for Social Change, Racist Victimization: International Reflections and Perspectives and many others. 6 Justification for the selected research design 6 DISCUSSION 7 Some Statistics and Background Information 7 History – Britain 7 Racial Profiling – a history 9 London Riots, 2011 9 Some Popular instances 12 ANALYSIS AND CONCLUSION 14 Racism in Metropolitan Police Service – An analysis 15 Conclusion 15 REFERENCES 17 INTRODUCTION Research Background No matter how much everyone condemns the idea of racism but it is seen that everyone encourages it in one way or the other and intentionally or unintentionally acts like a racist. T he phenomenon is so spread that even Metropolitan Police Service is not protected from it. There have been numerous incidents in the past that show that Metropolitan Police Service is racist in its attitudes and actions. Racism is the act of discriminating different races on the basis of different stereotypes attached with the races. Individuals have attitudes that they discriminate between people on the grounds of their races. When this discrimination takes the form of some kind of action and becomes inseparable with the acts of the institution then only it becomes institutional racism. This term will be used repeatedly in the course of this report (Scott, 1974, p. 6). Metropolitan Police Service, popularly known as the Met, looks after the territory falling in Greater London and deals with the crime and its causes in its territory. It also has the responsibility of helping in with the national targets of counter terrorism and protection of the British Royal Family and Government o fficials. Aims and Objectives of the research This research aims to identify instances in the past to verify whether Metropolitan police service has done racism in its actions or not. The research aims to look at some background information and history of racism in Britain and different developments made throughout the history in order to deal with this evil in the society. Furthermore, it aims to view some of the popular instants in which police showed racism in

Sunday, August 25, 2019

Video games as a for of art Research Paper Example | Topics and Well Written Essays - 1500 words

Video games as a for of art - Research Paper Example Why are they perceived as toys and not art? They are as beautiful as the works of arts we see in museums. Art is a manmade object, which is an illustration of an individual’s (artist) emotion and ideas that engage the audience’s emotions. Videogame engage people’s emotions and they are an imaginary world created by emotion and ideas of designers. It might not be made by artists or intended to be art, but that does not make it any less than a piece of art. Videogames even have more influence to people compared to a piece of art because you are in control, you make the calls, which engage an individual more. Have you ever walked into a class and look at the teacher for the full 45 minutes without understanding anything? Well, all people have been through that moment. A school in NYC uses only videogames to educate their students. All the students are paying attention and doing everything they could because they enjoy it. They are emotionally engaged in that videogame they are playing. Videogames are made to entertain people. They entertain people by engaging their emotions and feelings. Many people cried and laughed over a videogame. There are games that need the player to think in order to solve a riddle. Videogames create an imaginary world that an individual is ruling. As a player you’re the protagonist, you’re the king, you’re everything in the game. What is a better place to stay in other than the world you are ruling? As a player, you might like a game and praise the company that made it. What individuals do not think about are the people who made them (Robinson). A game is in a different world, with new building and new creatures that we never saw in real life, but where does all of that come from? It is all the imagination of an individual who spends 12 hours a day for about 4 or 5 year that is working on a game that his name will never be put into. Designers spend years making

Saturday, August 24, 2019

DQ6 Essay Example | Topics and Well Written Essays - 500 words - 1

DQ6 - Essay Example I have seen the leadership using its resources to coach, mentor and train the employees, which is indeed a positive point. However sadly I have also witnessed severe criticism on the part of the leadership towards the employees which has basically discouraged them in an out and out fashion. These two aspects however run hand in hand within the organizational undertakings. The role of ethics in the workplace is of immense significance. The reason for the same is that ethical leadership would ask of the employees to give in their very best and in line with the organizational norms and procedures. Ethics would ask of the employees to be true to their morals and thus remain in line with their value systems and principles which are indeed very significant from the personality building regimes. Ethical undertakings would suggest that an organization knows how to make best use of its resources and that too within the prescribed limits of the society. The workplace would be seen in a very pragmatic way and thus the negativities would be done away with at the earliest by the people who hold some form of grudges against the same. It is a fact that an ethical workplace would see more people vying to join the organization than a workplace which does not manifest ethical behaviors and actions (Yukl 2006). Employee diversity is changing the workplace in the present times since this aspect has brought together people from different nooks and corners of the globe. The strengths of these people are being basically judged more than anything else. It does not really matter from where these people have been brought together for the sake of achieving organizational goals and objectives. What matters most is how these talented people give in their very best towards completion of the tasks that have already been envisaged by the leadership domains in the organization. Diversity has meant growth and development for the organization and

Friday, August 23, 2019

Critical Management Systems - Mystery Shopping Essay

Critical Management Systems - Mystery Shopping - Essay Example The retail financial services, for instance, use Mystery shopping for two reasons – research into potentially high risk areas and identify key issues in areas of concern (FSA, 2006). The checklist should also reflect the key performance indicators which is a part of the organization’s vision and mission. Mystery shoppers should be independent, critical, objective and anonymous. Each location should be visited multiple times by different shoppers. While the employees should be notified that mystery shoppers would be around, the exact time and date should not be disclosed, which should remain a mystery (Kocevar-Weidinger, Benjes-Small, Ackermann & Kinman, 2010). The shopper however needs to be trained in evaluating employee behaviour and to ensure accurate data collection. The President of the Mystery Shopping Providers Association (MSPA) agrees that in-person visits can capture the â€Å"soft† issues that surveys often cannot: friendliness, courtesy, names, and knowledge (CRM Magazine, 2009). Facts emerge in a natural setting and this is not always possible in an interview or any other data collection method. Mystery shopping as a research tool helps to identify whether known customer requirements are met, to assess whether communications need to be improved and to check the consistency of standards across all branches (Beck & Miao, 2003). Calvert (2005), to evaluate the effectiveness of â€Å"mystery shopping† as a technique for service evaluation, interviewed public librarians in New Zealand who have used mystery shopping. Libraries used mystery shopping for three major reasons - improving process, improving staff behaviours, and benchmarking with similar organisations. It is used as a diagnostic tool to track the service delivery process; it is used extensively in staff appraisal and most importantly, organizations send mystery shoppers to rival firms to understand their service delivery process. This helps them to benchmark against the rivals. Mystery

Human ResourcesTraining and Development #2 Essay

Human ResourcesTraining and Development #2 - Essay Example SWOT Analysis is an effective tool in identifying the internal strengths and weaknesses and the external opportunities and threats. It helps to develop a plan of action to concentrate on weaknesses and threats and get maximum advantage from the strengths and opportunities it has. The strengths of Abbott Labs are: its great history of innovation, its wide range of products, the great respect it commands in market ratings, and finally its expanding geographical reach opening up new opportunities. These are certainly its strengths to build on. Its overdependence on the anti-bacterial Biaxin and the anti-epileptic Depakote is could be a major weakness for Abbott. Both these products contribute substantially to the company revenues and profits. The challenge for Abbott is to minimize the decline of sale of these two. Abbott has been doing it bests in exploring new opportunities and keeping its position of strength. The new agreements and acquisitions it has had with Knoll Pharmaceuticals, Vysis Inc, and Biocompatible will help expand its product range and its pipeline. The company signed a The price regulation of prescription drugs in various markets by peers and government agencies, strong competition from generic manufacturers, and the expiring patent protection are the major threats Abbott is facing. "Abbott Laboratories' 'Position of Strength'

Thursday, August 22, 2019

Bshs305 R2 Ethical Scenario Essay Example for Free

Bshs305 R2 Ethical Scenario Essay Read the following scenario: Shannon is a juvenile probation officer with the Department of Juvenile Justice. Recently, she covered her coworker, Janet’s client load, while Janet was on vacation. Shannon met with several of Janet’s clients. After meeting with clients, she discovered a pattern in which the clients would report that they have not seen Janet in 2 to 3 months. However, the case files reflected face-to-face contact with all of her clients, despite what her clients stated. When Shannon investigated further, she found that the client notes were all at the same day and time, which is unlikely. Further, several of Janet’s clients needed referrals for counseling, but Janet never completed them and has not followed up to ensure her clients are receiving the necessary services. Janet is a close friend of Shannon. Shannon does not want to get Janet in trouble but realizes something must be done. Answer, in a 75- to 100-word response, each of the following questions: 1. What are the ethical issues involved in the scenario? Human service professionals are obligated to provide high-quality service to their clients. Most codes of ethics indicate that the helper’s first responsibility is to enhance and protect the client’s welfare. One of the ethical standard is the human service professional’s responsibility to clients. Standard 2: â€Å"Human service professionals’ respect the integrity and welfare of the client at all times. Each client is treated with respect, acceptance, and dignity†. Unfortunately in this scenario Janet failed to respect her clients’ welfare. She not only had issues of breaking several ethical codes she literally failed her moral responsibility. 2. What client rights are involved in the scenario? The client has a right to actively participate in their treatment plan. They are privy to view their personal chart which would show them the fabricated notes of the helper. The system failed this client and the client is able to request for a new helper. Although the client has a right to a professional disclosure statement as to see the qualifications of his helper, chances are this helper would not disclose their unethical behavior. 3. What, if any, client rights were violated? I feel the clients rights were violated by the misguided treatment of the helper. The client was not treated with dignity, respect or integrity. They were violated in a as â€Å"helpers are ethically obligated to provide quality services†. Also the helping professional is committed to helping clients develop to the best of their abilities. The helper was not even servicing the client and in that aspect the client has been violated on several different levels of ethical codes. Ethical Decision Scenario BSHS/305 Version 2 2 4. How you would use the ethical decision-making model to address or resolve the situation? First of I would identify the problem which are two issues, first one is the clients are not receiving necessary services. Second issue is Janet lied on legal documents. I would review the ethical guidelines and consult with a co-worker as to how I should proceed with the probable course of action. I would then select the course of action and follow through with my obligation to assure clients receive due services and I would make sure Janet does not make this mistake again. I would report Janet’s actions to my supervisor and hope Janet understands that I am just doing my job.

Wednesday, August 21, 2019

Was Woodrow Wilson A Naive Idealist?

Was Woodrow Wilson A Naive Idealist? Wilson had a clear and definite vision for the USs future role in world affairs, as evidenced by his fourteen points speech, his overwillingness to compromise (in trying to further domestic program agenda, and at the Paris conference), and in his allowing the League of Nations to die when it did not fit his original plans. Wilsons ideas are used even to this day, where Americans, in any conflict regarding foreign policy, see themselves as the force of morality and their opponents as being evil, or corrupted. Also, Americans still believe in the need to spread the ideals of democracy around the world. The fact that Wilson has left so strong of a legacy on Americans shows that his ideals were not naà ¯ve, but instead very well thought out and comprehensive. Pro Summary: Wilson characterized as a noble idealist whose principles have made it difficult for later presidents to develop a foreign policy based on national self-interest. (Kissinger) Believed that Americas global influence was dependent on its selflessness Was able to take once isolationist US into war by first asserting to the public that his administration was devoted to peace. Affirmed that US sought no other gain than to vindicate its principles. Based foreign policy on moralistic ideals like the spread of democracy and spread of American principles as opposed to recognizing issues with balance of power. Had the conviction that the Anglo-Saxon race was superior and had the duty to remake world in their image He thought peace was based on universal law and national trustworthiness instead of equilibrium and national self-assertion. No other country has based international leadership on altruism instead of national interests. Entrance into WWI was not based on national interests at all but rather about moral foundations and abiding by the universal law. The effect of such a moral basis leads to total victory as the only valid goal so compromise is not possible. He didnt understand that the war was actually based on clashing of national interests and power struggle in Europe. Fourteen Points Speech- tried to affirm that war was being fought for moralistic ideals, as opposed to power struggle. He immaturely supported the idea of the League of Nations Believed in morality of the universe, and that nations of the world all interested in protecting peace He thought the war had resulted simply out of public ignorance bt the actual causes were much more complicated. Basic premise behind the League of nations was naive because in nearly all difficult cases nations tend to disagree about the nature of a threat or discrepancy ie. Italian aggressions and the Bosnian crisis Inflexible in ideals Caused by the moral foundation that he was built upon Inflexibility evidenced by tenure at Princeton, and his many strict changes to the school Con Summary: Wilson understood better than his nationalistic opponents the new international role that America would play in world affairs and was therefore not a naà ¯ve idealist. (Carleton) Wilson is being judged by personality traits: double standard at work. Wilson was said to be naà ¯ve even though he wanted to preserve a power balance by preventing Germany from being partitioned but FDR and TR supported harsh peace and forced unconditional surrender understood it. Long term program for America today is still based on Wilsonian liberalism- advocacy of American values like collective security, self-determination, and democracy At the Paris conference, European diplomats were impressed at Wilsons negotiating skills: compromised too much He repeatedly helped make compromises between liberals and conservatives in the Democratic Party and thus was able to pass the Federal Reserve Act, the Clayton Anti-Trust Law, the Federal Trade Commission, and more. In truth, Wilson compromised too much. Claim that he is stubborn is based entirely from fight in the Senate over ratification of the League of Nations Claim that he killed his own brainchild, the League of Nations, is unfounded in that Wilson knew that even if he attempted to appease the southerners, Lodge would eventually put enough reservations on it so as to emasculate it. Truly shows Wilsons determination and consistency in wanting to create a fully functional League Wilson had already attempted to satisfy Lodge with the inclusion of safeguards in the Leauge, but Lodge continued to use the Reservations to change the entire proposal If Wilson had tried to go on with Lodges reservations, other Nations probably wouldnt even join because of the fact that the other nations had to become signees before America even signed on, and thus they became suspicious of the agreement. Wilsons ideals and principles were not even naà ¯ve Wilsons peace without Victory speech demonstrates he had a clear understanding of the balance of power. Able to steer US from war with Mexico, despite tensions, and used diplomatic understanding to help the Mexican revolution be successful. He understood that the only way to prevent war in the future was through collective security- League of Nations. Comparable to todays UN Knew that dividing Germany would not help create a power balance. Able to keep up with need for domestic social reform Wilsons invasion of Haiti in 1915 ended bloody civil war Administration expanded American bureaucracy and was the inspiration for FDRs New Deal. The Treaty of Versailles was the best peace it could have been considering the circumstances and brought forth many revolutionary ideas: The mandate system helped prepare colonies for independence, preventing portioning of Germany, success in confining German responsibilities to civilian damage and Allied military pensions instead of the whole cost of the war.

Tuesday, August 20, 2019

Background And Pathophysiology Of Schizophrenia Psychology Essay

Background And Pathophysiology Of Schizophrenia Psychology Essay Schizophrenia is a severe chronic psychotic disorder associated with the brain and is characterised by symptoms classified into three major categories; positive, negative and cognitive symptoms. Positive symptoms include hallucinations, delusions and thought disorder. Negative symptoms consist of social withdrawal and flattening of emotional responses. In addition to this, deficits in cognitive function such as attention and memory are also often present in schizophrenic patients together with anxiety and depression. (Rang, 2007); (Lewis J A Lieberman 2000) Studies have shown several neurotransmitter systems such as serotonin, glutamate and dopamine to be involved in processes leading to the expression of the symptoms experienced in schizophrenia. Among these, the dopamine theory has received the most attention and it will be the focal point of this research. Serotonin, an essential neurotransmitter, has its place in explaining schizophrenia by trying to explain the elements of the disorder which were initially unexplained. This consisted of the negative symptoms and the actions of antipsychotics. Its role was recognised in the 1950s when it was discovered how similar serotonin was to LSD (lysergic acid diethylamide). LSD causes psychotic symptoms as it competes with serotonin and occupies its receptor sites. Atypical antipsychotics as well as blocking dopamine receptors, also act as 5-HT receptor antagonists. This hypothesis was confirmed when typical antipsychotics were combined with a 5-HT2 antagonist such as ritanserin. This resulted in relief of negative symptoms and extrapyramidal side effects. (Sadock, 2000) Glutamate has also been implicated in schizophrenia. This hypothesis is derived from evidence using PCP, a glutamate NMDA receptor antagonist. Administration produces psychotic symptoms and cognitive dysfunction in healthy subjects (Krystal et al. 1994) and negative cognitive symptoms in patients with schizophrenia. (Lahti et al. 1995) Phencyclidine, ketamine and dizocilpine, also glutamate NMDA receptor antagonists, provide psychotic symptoms in humans. Studies have also shown that there is reduction in glutamate receptor density and glutamate concentration in post-mortem brains of schizophrenic patients. (Rang 2007) The most common theory relating to schizophrenia is the dopamine one. The first formulation of the dopamine hypothesis suggests that excess mesolimbic dopamine is the reason for the positive symptoms. The evidence that this idea was based on included amphetamine abuse which increased synaptic dopamine leading to delusions (Laruelle et al. 1996) and that all antipsychotic drugs block dopamine D2 receptors. As this theory implied excess dopamine is responsible for positive symptoms, what is responsible for the negative and cognitive symptoms? Well, research has shown that negative and cognitive symptoms are the result of deficient dopamine in the pre fontal cortex due to D1 receptor dysfunction (K. L. Davis et al. 1991) There have been operational definitions of schizophrenia developed in an attempt the reliability of the diagnosis; The International Classification of Diseases (ICD-10) and The American Psychiatric Associations Diagnostic and Statistical method (DSM-IV-TR) and both contain lists of criteria but also insist that symptoms must have persisted for 6 months. PICTURE Schizophrenia usually presents itself in late adolescence or in early adult life (Kirkbride et al. 2006) with males having an earlier onset than females. In the UK, the mean age of first admission is about 22 years for men and 27 years for women. (Castle R M Murray 1991)Females also tend to have fewer negative symptoms and a better outcome than males. According to leading experts in this disorder, they have found that it is caused my many factors. One major factor is genetics, and schizophrenia occurs in 10% of people who have parents, brother or sister (first degree relatives) with the disorder. People who have grandparents, cousins or aunts and uncles (second degree relatives) also develop this disorder a lot more than the general public. (Kendler et al. 1993) Most importantly, the risk is at its greatest for a person who has a twin with schizophrenia. (Irving Gottesman 1991) PICTURE Several genes are related with the risk of schizophrenia but previously it was believed there is no particular gene that is responsible for the disease itself. Studies have shown that people with schizophrenia also have many rare gene mutations which involve many genes and disrupt the development of the brain. However in recent times, new research has shown there may be several susceptible genes. One such gene is DISC1 which could be linked to the development and treatment of schizophrenia. DISC1 plays a key role in the growth of individual neurons. Mutated Disrupted in Schizophrenia (DISC1) gene is seen to disrupt the growth and development of cells in the brain. When DISC1 levels were reduced in mice, cells in the brain failed to divide and the mice developed symptoms that mimicked schizophrenia in humans. (REFERENCE IMPORTANT ONE) Other than genes, environmental factors are probably important in the development of schizophrenia. These include exposure to infections, immunocompromised, stress and being in contact with toxic chemicals during childhood may slightly alter brain development. (Marcel ET AL REFERENCE 1999) Chlorpromazine was the first drug discovered to have antipsychotic properties, followed by haloperidol which was widely prescribed. This is an example of typical first generation medications and produced D2 receptor blockade. By 1980, second generation atypical drugs were out, most notably clozapine which was seen to be more potent in treating chronic patients. These had the benefits of also reducing negative symptoms and extreme side effects. Pharmaceutical companies in the 1990s started to take advantage of clozapine and develop drugs without its side effects and olanzapine is another popular atypical drug. In 2005, there was a study done known as the CATIE study, in the USA, comparing the effectiveness of antipsychotic drugs in clinical settings. It was seen that there were high rates of discontinuation; 64-82% over 18 months, due to patients not being able to tolerate side effects. Lack of efficacy was also found for all antipsychotic drugs in the study, although olanzapine was most effective (terms of discontinuation rates) than other drugs in the study. Despite this, olanzapine was associated with greater weight gain and increase glycosylated haemoglobin, cholesterol and triglycerides. These changes could have serious implications such as development of metabolic syndrome. (Jeffrey A. Lieberman et al. 2005) So why use or develop Chinese herb extracts as a therapeutic tool for schizophrenia? Although antipsychotic medication is still the foundation for the treatment in schizophrenia, it still leaves some people with unbearable side effects and distressing symptoms. The most common side effects are Parkinsonism, dystonia and akathisia and are most common with haloperidol and fluphenazine. (Schillevoort et al. 2001) (Levinson et al. 1990) Dystonic spasms affect the neck muscles tongue and face, and occur within a few days of treatment and are frequent at high doses. Akathisia is the restless leg syndrome and is characterised by great urges to move and difficulty in sitting still. Anti-cholinergic drugs can relieve these symptoms; they should not be given routinely as they also cause side effects such as blurred vision, constipation, dry mouth and euphoria. It is also important to remember that not all patients will get side effects from taking antipsychotics. Another long term side effect is tardive dyskinesia which is slow irregular movements particularly in the regions of the mouth, lips and protrusion of the tongue. Approximately 5% of the patients on antipsychotic medication developing this each year, but there is evidence that the incidence may be declining with increasing use of atypical antipsychotics. (Tarsy Baldessarini 2006) Due to the side effects, herbal medicines are commonly used for psychiatric purposes in both the developed and developing countries. (Walter Rey 1999) Studies have shown that some Chinese herbal medicines are effective for psychosis and that if used in conjunction with western medication, they enhance antipsychotic efficacy and reduce adverse effects. Another important aspect is that, Chinese herbs may be more accessible, acceptable and cheaper than drugs already available. Chinese herbal medication includes plants, fungi, resins, animal and mineral substances which are given within a formula which typically consist of 4 to 12 herbs. Administration is in the form of decoctions, pills, powders, tablets, phials and as standardized plant extracts. Chinese herbal medication has been known to treat schizophrenia for over 2000 years; although the methods used in Traditional Chinese medicine to diagnose and treat schizophrenia differs from that used in western medicine. In western medicine, it is usually diagnosed by criteria such as the Diagnostic and Statistical Manual (DSM) or the International Classification of Diseases (ICD) but in Traditional Chinese Medication, its diagnosed by the Chinese Classification of Mental Disorder (CCMD). Figure shows the difference between diagnosing and treating Schizophrenia using traditional and Chinese herbal medication Traditional Chinese medicine differentiates schizophrenia into syndromes which determine the course of treatment. Therefore if two people are to be diagnosed with schizophrenia could have different clinical features (syndromes) therefore will require different medications. Each syndrome has a specific herbal formulation, but patients typically have mixed clinical features therefore they require precise formulations made by adding or substituting herbs. (Rathbone et al. 2007) Hype or hope? Is there really a benefit of using Chinese herbs as a therapeutic tool of schizophrenia? There have been several clinical trials done using Chinese herbal medication in the treatment of schizophrenia. One of the earlier studies was done using Dang gui cheng qi tang as the herbal medication given to the treatment group without the addition of the antipsychotic chlorpromazine which the control group received. The setting was in a hospital and participants were divided into groups randomly. It was reported that no participants left the groups early and the result showed that the global state outcome not improved /worse favoured the control group receiving chlorpromazine. (Rathbone et al. 2007) These results should be treated with caution given design limitations such as it being only conducted for 20 days, but nevertheless do not support that herbal medication should be used by itself for the treatment of schizophrenia. Further research and trials have been done which has incorporated using herbal medication together with an antipsychotic versus an antipsychotic alone. In 1997, Chinese herbal medications Dang gui cheng qi tang or xiao plus an antipsychotic was given to a treatment group compared to just the antipsychotic given to the control group. The allocation was randomized, lasted for 12 weeks and included hospital as well as community setting. The result showed that the treatment group scored significantly lower for the outcome of global state not improved/worse than the control group. (Rathbone et al. 2007) Global data score from the Clinical Global Impression scale (a rating scale measuring severity of symptoms, treatment response and efficacy of treatment) also favoured treatment groups that took the herbal medication plus antipsychotic. Ginkgo biloba was used with an antipsychotic for the treatment group in 1996 (Rathbone et al. 2007) and Shui zhi and Da huang were used with chlorpromazine. There were side effects associated with taking antipsychotics and taking herbal medications with antipsychotics showed that extra pyramidal side effects still arose. Constipation was however lower in the treatment group. (Rathbone et al. 2007) In 2001, Zhang et al did a study giving a treatment group Ginkgo biloba with haloperidol with the control group only receiving the latter. When compared, the study showed there was no difference between treatment group and control group when comparing negative symptoms and also when looking at Brief Psychiatric Rating Scale scores. However, the scale of positive symptoms did marginally favour the treatment group. (Rathbone et al. 2007) For all studies done in the past, we have to be aware that application of Chinese herbal medication is based on syndrome differentiation with failure of applying this differentiation resulting in ineffective or harmful treatment. There is no concrete evidence that when given alone, Chinese herbal medications offer benefits which are equal or even greater than antipsychotic drugs. When the herbal drugs are used with antipsychotics, they may offer improvement in symptoms but as there is still limited evidence in regards to Chinese herbs and traditional Chinese medication, this approach must still be considered new and more investigation is needed. Stepholidine is an active ingredient of the Chinese herb Stephania intermedia Lo, and belongs to an alkaloid group tetra-hydroberberine. (S. X. Xu et al. 1989) Initial research had shown that Stepholidine decreased blood pressure without exerting any adverse effects on the heart as well as exhibiting analgesia and any sedating effects on the central nervous system. Recent studies have shown stepholidine to be a pioneering drug in the treatment of schizophrenia because it is a dopamine D1 receptor agonist and a D2 receptor antagonist. Due to the pathogenesis of this disease suggests the dysfunction of D1 receptors in the medial prefrontal cortex, which is accompanied by hyperactivity of D2 receptors in subcortical regions such as ventral tegmental area (VTA) and the nucleus accumbens (NAc), when developing a antipsychotic drug should possess dual agonistic and antagonistic actions on the receptor. Stepholidine and its analogues tick these two important boxes. Stepholidine acts through D1 receptors to increase adenylyl cyclase activity and subsequent signalling pathways regulated by adenylyl cyclase might be responsible for the physiological responses, including rotational behaviour and changes in the firing activity of the neurons induced by Stepholidine. By contrast, Stepholidine inhibits both D2 auto-receptor mediated feedback inhibition of dopamine containing neurons and D2 receptor mediated effects on target non dopamine containing neurons. (Guo-Zhang Jin et al. 2002) There are several symptoms related to schizophrenia and insomnia is one of the most common. This could be partly related to the over-activity of the dopaminergic system. There has been a study done to show whether stepholidine modulates sleep behaviours. This was done in mice and the sleep-wake profiles were observed. From this study it has been concluded that stepholidine significantly increased the amount of NREM sleep and prolonged the duration of NREM sleep episodes, with reduction in the amount of wakefulness. Stepholidine had no effect on either the amount of REM sleep. Because it maintains NREM sleep in mice, it is suggested that it has the potential to be also used in the treatment of insomnia. (Qiu et al. 2009) Figure 1 shows the dual action of Stepholidine. Dopamine (DA)-containing neurons in the ventral tegmental area (VTA) project to the nucleus accumbens (NAc) and medial prefrontal cortex (mPFC). The schizophrenia hypothesis suggests that D1 receptor dysfunction in the mPFC leads to the negative symptoms of schizophrenia and the D2 receptor hyperactivity in the sub-cortex nuclei leads to the positive symptoms of this disorder [1-4]. The D1 receptor agonist effect of SPD in the mPFC is suggested to ameliorate the negative symptoms of schizophrenia, whereas the D2 receptor antagonist effect of SPD that predominates in the sub-cortex would improve the positive symptoms The Stanley Medical Research Institute (SMRI) awarded a grant of Canadian $330,000 to Dr. Shitji Kapur and Dr. David Mamo in 2006 to study L-Stepholidine. The work they would do would be built up from previous knowledge of the drug already known. They conducted preclinical studies in rats and it showed to be a very promising compound. The goal then was to give it to humans and measure its D2 binding in an attempt at showing it indeed is a D2 drug in vivo using PET, and also estimate its expected therapeutic dose for future clinical studies. Having had several correspondences Dr Mamo, he has informed me that the main company in China had stopped the production of Stepholidine and for ensuring that the compound is pure without any contaminants and to assure the local regulatory authority the research was a safe study, they decided not to use stepholidine from China. Dr Kapur and Dr Mamo then collaborated with a chemist to synthesize stepholidine in a lab. Synthesis was fine, but the pr oblem was that they couldnt scale up the production to gram scale. A chemist had told him with further work, production was possible, but the SMRI was not willing to wait for this. The funding had to be given up but not for the reason that the drug wasnt showing promise. Another drawback in stepholidine is its bioavailability. Drugs given orally, acting on the central nervous system, should have good bioavailability and good blood brain barrier penetration. In rat based assays, it was seen that stepholidine, when administered orally, was poorly available to systemic circulation but could cross the blood brain barrier easily, resulting in good entry into the brain. Stepholidine was also found to have good permeability of the membrane that was not affected by efflux transporters such as P-gp or MRP2. Stepholidine which was absorbed from the gastrointestinal tract was also rapidly eliminated by glucuronidation of phenolic hydroxyl group, and less by sulphation, methylation, demethylation and /or N-oxidation. This poor bioavailability achieved by stepholidine could be due to the extensive pre systemic metabolism. A way to overcome this would be to develop pro-drugs, which would be chemically modified versions of stepholidine which will undergo enzymatic or chemical transformation for the active drug to be released. Example of this might be to modify the hydroxyl groups of stepholidine. (Sun et al. 2009) Due to its poor bioavailability, there has been significant development in recently towards the modification of stepholidine by development of series of derivatives. One derivative that has improved bioavailability while maintain the pharmacological properties of stepholidine, is bi-acetylated l-stepholidine. In recent times, although there has been an increase in material prosperity and growing success of traditional western medication, there has been an overall increase in psychotic disorders especially schizophrenia. Psychiatric patients not only want their symptoms to disappear, they also want to continue to lead a normal life without all their troubles. Psychiatric patients have better resources for the treatment now than ever before, but due to frequent disappointments in western medication especially due to its side effects; there has been increased growth of alternative and complementary methods in the treatment of patients. Sometimes patients also seek help from spell breakers, exorcists and herbalists. In recent times, according to the World Health Organisation (WHO) approximately 80% of people in the world have relied on herbs in satisfying their medical care needs, and developed countries such as Germany, Italy and even the USA have shown a dramatic increase in herbal medicine consumption. Stepholidine had led the way in recent drug discovery with it being both a D1 receptor agonist and D2 receptor antagonist activity. This is a unique pharmacological characteristic of DH-THPBs (dihydro) and will be vital in the future when developing new antipsychotic drugs. More so, another DH-THPB, 12-chloroscoulerine has been found to have more potent dual action than stepholidine. In this project, I will analyse research done with stepholidine in regards to it being a therapeutic tool in the treatment of schizophrenia. Word count 2,992

Monday, August 19, 2019

A Critique of DiLorenzos The Real Lincoln Essay -- Thomas J. DiLorenz

A Critique of the Real Lincoln The Real Lincoln: A New Look at Abraham Lincoln, His Agenda, and an Unnecessary War, by Thomas J. DiLorenzo completely shatters the illusion of the 16th President as the liberator of the slaves. DiLorenzo provides convincing evidence for Lincoln’s overt racism as expressed in his documented views on racial supremacy as stated in his desire to colonize all American blacks outside the United States (p. 4); Lincoln’s views were matched by the majority in the North who used such tools as state constitutional amendments to prohibit the emigration of black people into Northern states like Lincoln’s home of Illinois (p. 4); and that the Presidents war which killed 620, 000 Americans and destroyed 40% of the economy, was a singularly terrible, unjustified conflict given the proven success in the 19th century of the peaceful end to slavery through the policy of compensated emancipation (p. 4). DiLorenzo accordingly notes that, â€Å"Between 1800 and 1860, dozens of count ries, including the entire British Empire, ended slavery peacefully; only in the United States was war involved (p. 4). DiLorenzo documents that history’s claims that the abolition of slavery as the leading motive behind the Union’s aggression against the South is untrue. He states that Lincoln’s motives were economic and political and in no way altruistic. Lincoln did oppose slavery, but his opposition did not stem from any moral motive. He wished to preserve white labor, and to avoid artificial inflation of Southern representation in Congress under the three-fifths clause of the Constitution, under which every five slaves counted as three free persons for the purpose of allotting number of congressional seats. DiLorenzo explains that from th... ...ding Fathers had tried to institute through the Declaration of Independence and the U.S. Constitution. Thomas DiLorenzo does a good job in documenting Lincoln’s ruthlessness and hypocrisy and how historians have covered it up. The founding fathers had a fear of federal governmental abuse. They saw state sovereignty as a protection. That’s why they gave us the Ninth and Tenth Amendments. I found this book very interesting and it makes you wonder what else we may have learned growing up that could be completely untrue according to your elementary school history books. I do however understand that there is two sides to every story and I wish DiLorenzo did a better job at explaining why history has painted Lincoln as such a hero. Works Cited DiLorenzo, Thomas. The Real Lincoln: A New Look at Abraham Lincoln, His Agenda, and an Unnecessary War. Three Rivers Press, 2003.